Extracts of Horehound leaves and wild cherry bark cause apoptosis and cell growth suppression in cancer cells

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Extracts of Horehound leaves and wild cherry bark cause apoptosis and cell growth suppression in human colorectal cancer cells according study published in national peer review medical journal, PubMed Central

The report shows that extracts of anti-inflammatory horehound leaves and wild cherry bark exhibit anti-proliferative activity in human colorectal cancer cells. Both horehound and wild cherry extracts cause suppression of cell growth as well as induction of apoptosis.

Our data show that anti-inflammatory M. vulgare (horehound) leaves and P. serotina (wild cherry) bark extracts have anti-proliferative activity in human colorectal cancer cells and the mechanisms may involve enhanced NAG-1 expression and/or down-regulation of ?-catenin signaling.

Published in final edited form as: Oncol Rep. 2006 January; 15(1): 275–281

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